Poster Walks

Those presenters selected for a Poster Walk should assemble in front of the indicated kiosk at the start of each Poster Walk Session. The walk leaders will moderate the sessions and each presenter should be prepared to present his/her electronic poster from a tablet computer connected to a large screen (microphone available). Please ensure you have submitted your electronic poster ahead of the meeting!

Expect to speak for 3-4 minutes and answer a couple of questions from the group.

These sessions are open to all delegates so even if you are not presenting, please feel to join a group.

Date Time Poster Walk Number Session Poster Number Title Presenter Kiosk Number Kiosk Location Leader
Friday 29 September 2017 11.30-12.25 01

Epidermal Structure and Function 1

      01 2nd Floor Sirkku Peltonen
        089 MiR-30a is an aged-related microRNA that impairs differentiation and induces apoptosis in human epidermis Charlotte Muther      
        096 PRC2 complex is required for human epidermal differentiation and proliferation. Andrei Mardaryev      
        104 In reconstructed human epidermis, peptidylarginine deiminase inhibitor Cl-amidine modulates cornification and keratinocyte autophagic flux Michel Simon      
        106 Three-dimensional agent-based modeling of the human epidermal structure and barrier function with realistic cell morphology Georgios Stamatas      
        111 Cornification of normal epidermal keratinocytes is preceded by the expression of specific interleukin-1 family members Leopold Eckhart      
        112 Real-time imaging of calcium dynamics in human epidermis in response to point laser stimulation Makiko Goto      
        113 Immortalized N/TERT keratinocytes: an excellent and versatile alternative for primary keratinocytes in experimental dermatological research Jos Smits      
        132 Design of an in vitro skin 3D model mimicking a disruption of the barrier function Pauline Rouaud-Tinguely      
Friday 29 September 2017 11.30-12.25 02 Inflammation, Immunity and Infection 1: Allergic contact dermatitis, atopic dermatitis       03 2nd Floor Thomas Werfel
        105 An acute AD-like phenotype facilitates allergen sensitization and aggravates experimental asthma in barrier-impaired FlgHrnr-/- mice Andrea Braun      
        183 Genome wide association identifies MAPKinase pathway regulators as key genetic determinants of allergic contact dermatitis. Kiarash Khosrotehrani      
        295 Epidermal growth factor relieves inflammatory signals in Staphylococcus aureus treated human epidermal keratinocytes and atopic dermatitis-like skin lesions in Nc/Nga mice. You Jin Lee      
        299   Development of a novel, perceived stress-sensitive humanized mouse model of atopic dermatitis Amos Gilhar      
        317 PD-L1 on radio-resistant cells regulates effector CD8+ T-cell activation during the elicitation phase of contact hypersensitivity Tomoko Hirano      
        323 NecroX-5 Ameliolates Atopic dermatitis like Skin Lesions of NC/Nga Mice Ji Hyun Lee      
        346 High biofilm-producing Staphylococcus aureus associates with severe atopic dermatitis and its proliferation is increased by inflammatory cytokines Enea Gino Di Domenico      
        347 Regulated expression of CD73 by subsets of dendritic cells in skin is crucial for modulating contact hypersensitivity reactions in mice. Karsten Mahnke      
        350 Efficacy of Topical Endocannabinoid Membrane Transporter Inhibitor WOL067-531 in a Double Blinded, Placebo Controlled Crossover Study in a Colony of Atopic Beagles Michael Soeberdt      
        374 Epicutaneous allergen exposure induces pathogenic IL-22-producing T helper cells Melanie Carevic      
        386 The genetic diversity of Staphylococcus aureus colonisation in atopic eczema disease flare. Catriona Harkins      
Friday 29 September 2017 11.30-12.25 03 Inflammation, Immunity and Infection 2: Autoimmune bullous dermatosis; vitiligo       05 2nd Floor Michael Hertl
        324 IL-17A is a key regulator in experimental bullous pemphigoid Lenche Chakievska      
        335 Multicenter prospective study on multivariant diagnostics of autoimmune bullous dermatoses using the BIOCHIPTM technology Nina van Beek      
        355 NKG2D is highly expressed on IFN? producing skin CD8+ effector memory T cells in vitiligo Katia Boniface      
        358 Treg dysfunction leads to spontaneous production of autoantibodies to bullous pemphigoid antigens in mice Ken Muramatsu      
        362 Treg deficiency leads to development of BP230-autoantibody mediated autoimmune blistering disease Stefanie Häberle      
        370 Anti-desmoglein 3 autoantibodies cloned from the IgA1 repertoire of an IgA pemphigus patient are directly pathogenic, but not sufficient for disease induction Shirin Emtenani      
        383 Vitiligo skin is imprinted with resident memory CD8 T cells expressing CXCR3 Katia Boniface      
        391 Anti-type 7 collagen antibodies identifies a subpopulation of BP patients with relapse Frank Antonicelli      
        395 In vitro expansion of desmoglein-specific B cells of patients with pemphigus Hiraku Suga      
Friday 29 September 2017 11.30-12.25 04 Inflammation, Immunity and Infection 3: Psoriasis       09 2nd Floor Marta Szell
        314 Infiltration of MDR-1-expressing T cells including Th17 in psoriasis lesional skin and their association with corticosteroid resistance Toshiharu Fujiyama      
        315 IL-36y is a strong inducer of IL-23 production and angiogenesis in psoriasis Charles Bridgewood      
        322 Dysregulation of Akt-FOXO1 pathway leads to Dysfunction of Regulatory T Cells in Psoriasis Patients Bing Li      
        325 The short chain fatty acid sodium butyrate attenuates imiquimod-induced psoriasis-like skin inflammation Anika Bruhs      
        327 Galectin-3 in keratinocytes participates psoriasis development by recruiting neutrophils into epidermis Liangchun Wang      
        337 Downregulated Caveolin-1 expression in monocytes may contribute to the pathogenesis of psoriasis. Naoko Takamura      
        341 Mechanical stretch contributes to the pathogenesis of psoriasis by regulating the phenotype of keratinocytes Pei Qiao      
        344 Opposing effect of TRPA1 and TRPV1 on imiquimod-induced psoriasiform dermatitis Agnes Kemeny      
        348 Topical RORγ inverse agonist alleviate preclinical models of psoriasis Feriel Hacini-Rachinel      
        365 Myeloid but not plasmacytoid blood DCs possess Th1 polarizing and Th1/Th17 recruiting capacity in psoriasis Anikó Kapitány      
Friday 29 September 2017 11.30-12.25 05 Inflammation, Immunity and Infection 4: Keratinocytes, inflammation and related aspects     11 2nd Floor Karin Loser
        191 Characterization of the interaction of desmoplakin with keratins and desmin: implication for genetic cardio-cutaneous syndromes Bertrand Favre      
        306 Keratinocyte-specific ablation of MCPIP1 is sufficient to aggravate skin inflammation Piotr Konieczny      
        308 Epidermal keratinocytes regulate bacterial immune responses and host defense through EGFR Thomas Bauer      
        332 Non-conventional T-cells in the pathogenesis of alopecia areata: Targeting iNKT10 cells with ?-galactosylceramide Amos Gilhar      
        339 Senescent human fibroblasts selectively secrete miRNAs in extracellular vesicles and modulate keratinocyte functionality during skin aging Lucia Terlecki-Zaniewicz      
        361 Modulation of T lymphocytes by Simvastatin: Possible Role in Alopecia Areata Treatment Joaquin Jimenez      
        369 Newly discovered function of reduced-HMGB1 as an inflammation suppressor in keratinocytes Hideki Mori      
        378 Hapten-induced tertiary lymphoid organ-like structures in the scalp treated with topical immunotherapy for alopecia areata. Yohei Natsuaki      
        380 The role of C5a-C5aR1 axis in keratinocyte activation Rintaro Shibuya      
        394 Analysis of keratinocyte response to Trichophyton rubrum dermatophyte infection in a model of reconstructed human epidermis Emilie Faway      
        405 STAT3 activation causes IL-33 expression in normal human epidermal keratinocyte Hidetoshi Tsuda      
Friday 29 September 2017 11.30-12.25 06 Wound Healing and Tissue Remodelling 1       12 2nd Floor Teresa Odorisio
        661 Mechanisms that regulate adipocyte stem cell behavior in the skin Guillermo Rivera Gonzalez    
        666 Interferon-? deficiency attenuates skin fibrosis in a murine model of chronic graft-versus-host disease-like scleroderma Akimasa Saito      
        667 A novel TGF-beta/Smad signaling inhibitor ameliorates bleomycin-induced skin fibrosis Minoru Hasegawa      
        672 Therapeutic potential of the Nox1/4 inhibitor GKT137831 in Systemic sclerosis Heba Dosoki      
        673 Dysregulation of MicroRNA Biogenesis in Diabetic Skin Teresa Odorisio      
        676 Follistatin, an antagonist of activin, as a novel treatment in keloid disease Seungmin Ham      
        678 Integrated Metabolome-Microbiome Analyses to Evaluate the Alleviating Effects of Short-term Green Tea Supplementation for UVB-induced Erythema Eun Sung Jung      
        682 Development of a 3D living skin equivalent to explore the influence of senescence on the skin ageing phenotype Deborah Milligan      
        683 New ex-vivo model containing the 3 layers of the human skin and mimicking fibrosis in adipose tissue Richard Fitoussi      
Friday 29 September 2017 11.30-12.25 07 Melanoma and other Skin Cancers 1: Lymphoma; Basic aspects       16 3rd floor Eugene Healy
        201 Targeting tropomyosin receptor kinase (TRK) in CYLD defective tumours: A placebo-controlled early phase trial with pegcantratinib. Neil Rajan      
        522 Blocking CD137-CD137L interactions inhibits proliferation and survival of cutaneous T-cell lymphoma cells via hampering several signaling pathways Hiroaki Kamijo      
        531 Galectin-9 induces apoptosis of tumor cells through caspase pathways in cutaneous T-cell lymphoma Rina Nakajima      
        535 CD147-cyclophilin A interactions promote proliferation of cutaneous T-cell lymphoma Minami Sakamoto      
        543 Multiple cancer-related genes are mutated in p53 mutant patches in human skin. Eugene Healy      
        551 Analysis of pruritous factor in cutaneous T cell lymphoma Eiji Kiyohara      
        552 HMGB1 levels are increased in lesional skin and sera in patients with erythrodermic cutaneous T-cell lymphoma Naoyuki Senda      
        554 Dissecting fibroblast heterogeneity in skin cancer Beate Lichtenberger      
        556 TIGIT-CD155 interaction regulates NK and CD8+ T cell-mediated antitumor responses in patients with cutaneous T-cell lymphoma. Naomi Takahashi      
        568 Investigation of the role of type VII collagen in the HIF1α induced pro-angiogenic pathway Matthew Caley      
Friday 29 September 2017 11.30-12.25 08 Genetics and Cell Based Therapy 1       17 3rd floor Andrew South
        178 Cooperation of keratin mutations and posttranslational modifications Melanie Homberg      
        184 Sirolimus interferes with the calcium influx to reduce the neuropathic pain in Fabry disease Yang Pan      
        187 Genetic Diagnosis of Pachyonychia Congenita and Keratoderma Frances Smith      
        188 Psoriasis Stratification to Optimise Relevant Therapy (PSORT): Genome-wide study reveals genetic drivers of response to biologic therapy in psoriasis Nick Dand      
        193 Integrating health records and genetic signatures to enhance psoriatic arthritis risk assessment Matthew Patrick      
        196 New keys for the pathophysiology of Peeling Skin Disease revealed by transcriptomic analyses of two Corneodesmosin-deficient mouse models Sarra ZaafouriI      
        197 Chromosomal inversions as a hidden disease-modifying factor   Toshifumi Nomura      
        198 TALEN-mediated gene editing in epidermolytic ichthyosis patient-derived keratinocytes Oliver March      
        199 Impairment of notch 1 signaling is a common defect in lesions from patients with hidradenitis suppurativa Herve Bachelez      
        207 Improving diagnostic yield for filaggrin; hidden mutations in the Dutch population Michel van Geel      
        208 Targeting Plasma Pyrophosphate Deficiency in Mouse Models of Heritable Ectopic Mineralization Disorders – PXE and GACI Jouni Uitto      
Friday 29 September 2017 11.30-12.25 09 Photobiology and Pigmentation 1       18 3rd floor Hamid Reza Rezvani
        413 Epigenetics modification and autophagy associated to UV radiations on skin models. Elisa Caviola      
        621 Melanocytes sense blue-light and regulate the pigmentation through the Opsin 3 Thierry Passeron      
        622 The novel factor Active Breakpoint Cluster Region-Related Protein (ABR) contributes to melanocyte migration Motonori Kurosumi      
        623 The influence of photoirradiation on the circadian clock genes in human keratinocytes and melanocytes Shinnosuke Muramatsu      
        628 Dual vibration resonance frequency CARS microscopy imaging of basal cell carcinoma to achieve stain free histopathology Norbert Kiss      
        629 Suppression of autophagy by Tyrosinase-Cre–mediated deletion of Atg7 leads to accumulation of p62/sequestosome 1 in pigment cells and neurons Leopold Eckhart      
        632 Photoprotection by constitutive melanin: correlating deoxyribonucleic acid damage in vivo and skin cancer incidence. Damilola Fajuyigbe      
        634 Involvement of Near-infrared Radiation in Sebaceous Hyperplasia in the Skin of Hamsters Noriko Akimoto      
        638 Photochemotherapy limits Treg plasticity and restores Treg function in psoriasis patients Kan Torii      
Friday 29 September 2017 11.30-12.25 10 Hair and Other Adnexal Structures 1: Hair        20 3rd floor Marta Bertolini
        244 Defective maintenance of hair follicle stem cells through COL17A1 loss   orchestrates the hair follicle aging program Hiroyuki Matsumura      
        249 Innovative hair care biomimetic peptide: a promising solution to promote hair pigmentation and counteract the graying hair process Joan Attia      
        251 Morphogenetic Events in Hair Follicle Heterotypic Spheroids Ekaterina Kalabusheva      
        255 Bone Morphogenetic Proteins are Critical Factors for Hair Follicle Epithelial–mesenchymal
Interactions in Androgenetic Alopecia
María Balañá      
        261 Tissue and circulating microRNA co-expression analysis reveals potential involvement of miRNAs in the pathobiology of frontal fibrosing alopecia Christos Tziotzios      
        263 (-)-cannabidiol differentially influences hair growth Imre Szabó      
        264 CCR5 blockade shows prevention of alopecia areata development as well as improvement of alopecia areata Taisuke Ito      
        268 Male-pattern baldness and its association with coronary heart disease. Stefanie Heilmann-Heimbach    
        269 The PPAR-γmodulator, N-acetyl-GED, protects from epithelial-mesenchymal-transition to human hair follicles: potential relevance for scarring alopecia Marta Bertolini      
Friday 29 September 2017 14.35-15.30 11 Epidermal Structure and Function 2       01 2nd Floor Salvador Aznar-Benitah
        101 Cannabinoid receptor 1 (CB1) is a novel negative regulator of keratinocyte mitochondrial function in human epidermis ex vivo Attila Oláh      
        109 Nicotinamide metabolism controls the proliferation/differentiation balance in Human Primary Keratinocytes Chye Ling Tan      
        118 Leucine-rich alpha-2-glycoprotein 1, which is down-regulated during skin aging, plays a role in the maintenance of extracellular matrix integrity Seung-Taek Lee      
        121 The role of Runx family in the murine epidermis Eisaku Ogawa      
        123 The fatty-acid chain length of ceramides is negatively affected by chronic UV exposure. Seung Phil Hong      
        125 Characterization of TSG-6 protein in healthy and inflammatory models of reconstructed human epidermis Céline Evrard      
        126 The selective serotonin reuptake inhibitor fluoxetine exerts anti-inflammatory actions on human epidermal keratinocytes Kinga Tóth      
        130 Deciphering the role of the hexosamine pathway in skin homeostasis Kira Allmeroth      
Friday 29 September 2017 14.35-15.30 12 Epidermal Structure and Function 3       03 2nd Floor Daniele Bergamaschi
        093 Towards modeling ethnic variations in sebaceous lipid production using human iPSC derived sebocytes Julien Maruotti      
        094 Prostaglandin E2 regulates osteoclastogenesis through the induction of RANKL in middle ear cholesteatoma. Ryusuke Imai      
        099 E-Cadherin is dispensable for epidermal localization of Langerhans cells Britta Dorn      
        103 Skin Metaproteomics: Understanding function of our microbial part. gilbert skorski      
        110 Transglutaminase 2 is a potential regulator of sebocyte maturation Dora Kovacs      
        116 Comparative transcriptomic analysis of fibroblasts from two sisters with discordant severe generalized recessive dystrophic epidermolysis bullosa phenotype reveals new molecular markers associated with disease severity. Esteban Chacón-Solano      
        127 Propionibacterium acnes regulate the properties of the keratinocyte barrier by modulating the expression of tight junction proteins Beáta Bolla      
        265 Loss of Langerhans cells in scar lesion of lichen planopilaris is caused by downregulation of integrin αvβ6 in the epidermal keratinocytes Manao Kinoshita      
Friday 29 September 2017 14.35-15.30 13 Inflammation, Immunity and Infection 5: T cells, myeloid cells, mast cells       05 2nd Floor Luis Santamaria Babi
        319 Resistant Residents: Turnover of Skin-Resident Memory T cells Johanna Strobl      
        330 Deficiency of Bach2 results in improved tumor immunity by enhancing effector function in CD8 T cells Yuki Sato      
        336 Tumour Associated Macrophage Recruitment in SCC Matthew Caley      
        352 Neuromedin U directly activates human and mouse skin mast cells Yoshimi Matsuo      
        356 An Anti-inflammatory Role for ALK3 in Langerhans Cells Mathias Hochgerner      
        359 Program cell death-1-ligand 1 blockade leads to MHC class I dependent IL-17 response in cocultures of CLA+/ epidermal cells activated by Streptococcal pyogenes in psoriasis Luis Francisco Santamaria Babí    
        366 Epidermal delivery of polyinosinic-polycytidylic acid in a human skin explant model activates the MDA5/MAVS pathway in Langerhans cells Pooja Tajpara      
        388 Sorafenib enhances mast cells maturation and degranulation in human skin Yukari Mizukami      
        392 IL-2, IL-4 and TGF-beta promote the differentiation of IL-9-producing T cells from healthy human skin Philip Kienzl      
        393 Myeloid cells alter their effector status in response to the secretome of senescent cancer cells Katharina Böhm      
        407 Glucocorticoids suppress TLR2/1-induced inflammation while maintaining host defense responses in human macrophages Mario Fabri      
Friday 29 September 2017 14.35-15.30 14 Inflammation, Immunity and Infection 6: Psoriasis       09 2nd Floor Enikö Sonkoly
        095 Loss of loricrin exacerbates psoriasis-like skin inflammation through altered dendritic cell homeostasis Yosuke Ishitsuka      
        351 Keratin 17 is ubiquitinated by Trim21 in human keratinocytes in psoriasis Luting Yang      
        354 Identification of the epidermal miRNome in psoriasis skin Enikö Sonkoly      
        357 The role of the galanin system in psoriasis-like skin inflammation Felix Locker      
        373 Interleukin-17 modulates endothelial cell/keratinocyte cross-talk in psoriasis Cristina Failla      
        375 Psoriasis-like inflammation in K14PPAR?/? transgenic mice selectively overexpressing PPAR?/? in keratinocytes. Frédéric Dezoteux      
        376 Is neutrophil the dominant IL-17 producer in psoriasis? Keiichi Yamanaka      
        385 IL-17E activates M2 macrophages to produce IL-8 in a p38 dependent manner and favor the recruitment of neutrophils in psoriatic skin. Luisa Senra      
        390 SERPINB2 is regulated by the NF-?B pathway and miR-146a in human primary keratinocytes and psoriasis Helen Hermann      
        399 IL-36 receptor antagonistic antibodies inhibit inflammatory response in IL-23 model of psoriasiform dermatitis Viktor Todorovic      
Friday 29 September 2017 14.35-15.30 15 Inflammation, Immunity and Infection 7: Bacteria, viruses and antimicrobial peptides       11 2nd Floor Thomas Volz
        326 Resistin-like molecule α (relmα) is a skin antimicrobial protein that is regulated by vitamin A Tamia Harris-Tryon      
        334 Molecular, morphological, and metabolic background of newly proposed three subspecies of Propionibacterium acnes Itaru Dekio      
        349 Induction of IL-10-balanced immune profiles following exposure to LTA from Staphylococcus epidermidis Thomas Volz      
        372 Anabotulinum toxin reduces LL-37 induced rosacea inflammation by blocking mast cell degranulation Anna Di Nardo      
        377 Propionibacterium acnes CAMP factor 1 recognized Toll-Like Receptor-2 Philippe Grange      
        384 Rosacea-associated bacteria induce plasmacytoid dendritic cell-derived type I interferon driving flare-ups of disease Alessio Mylonas      
        387 In-vivo analysis of bacterial antigen delivery dynamics and T cell immunity against Staphylococcus aureus skin infection Gyohei Egawa      
        400 Isomerization of urocanic acid by ultraviolet radiation and its role in modulation of skin microbiome, antimicrobial peptides, and immune function VijayKumar Patra      
        409 Signal deficiency of melanocortin-1 receptor augments extent of skin infection induced   by S. aureus Heba Dosoki      
        410 Cross-talk between non-immune and dendritic cutaneous cells: new insights into inflammatory responses to S. aureus. Pauline Rouaud-Tinguely      
Friday 29 September 2017 14.35-15.30 16 Inflammation, Immunity and Infection 8:  Fibrosis, sclerosis and related diseases       12 2nd Floor Kerstin Steinbrink
        304 Inhibition of p38 MAP kinase suppresses murine Sclerodermatous Chronic Graft-Versus-Host Disease Takashi Matsushita      
        305 Fli1 deficiency alters the phenotype of dermal dendritic cells, promoting the development of dermal fibrosis in bleomycin-treated mice Shunsuke Miura      
        331 Single cell analysis reveals diversity of phenotype and function of autoantigen-specific B cells in systemic sclerosis Ayumi Yoshizaki      
        338 Pro-fibrotic Phenotype of Human Skin Fibroblasts Induced by Periostin via Modulating TGF-β Signaling Miwa Kanaoka      
        364 Lymph node stromal cell-mediated deletional tolerance controls the development of GVHD-like skin lesion in newly generated involucrin-mOVA mice Yujin Nakagawa      
        381 Fli1 deficiency promotes CXCL13 expression from macrophages, contributing to the development of systemic sclerosis Yoshihide Asano      
        382 Poly(lactic-co-glycolic acid) (PLGA) nanoparticles containing pioglitazone attenuate bleomycin-induced skin fibrosis. Mai Kanemaru      
        402 Serum levels of genomic DNA of ?1(I) collagen are detectable and elevated in scleroderma patients Soichiro Sawamura      
Friday 29 September 2017 14.35-15.30 17 Melanoma and other Skin Cancers 2: Melanoma        16 3rd floor Lionel Larue
        525 ADAM9 modulates melanoma development and metastasis Paola Zigrino      
        530 Deciphering tumour heterogeneity towards optimised characterisation of malignant melanoma Johannes Griss      
        534 Predicting prognosis of BRAF mutated melanoma due to analyzing immune response Kenta Nakamura      
        539 Immunotherapy against Metastatic Melanoma with iPS Cell-Derived Myeloid Cell Lines Producing IFN-β or IL-15 Yosuke Kubo      
        541 p63 signalling in BRAF inhibitor resistant melanoma Ankit Patel      
        544 Prognostic biomarkers based on melanoma cell-lines in stage III melanoma patients Anne KNOL      
        546 Immune biomarkers to predict response of nivolumab, intratumoral gene expression and T cell receptor repertoire analysis Satoshi Fukushima      
        547 FOXD1 is overexpressed in melanoma but not in melanocytic nevi, and associated with melanoma cells proliferation Masahiro Hayashi      
        550 Raf kinase inhibitor protein down regulation does not modify malignant properties of V600E BRAF mutated melanoma cells Cristina Penas Lago      
        567 Ultraviolet (UV)-A irradiation induces changes in metabolism which influence, via enhanced Warburg effect, melanoma invasion York Kamenisch      
Friday 29 September 2017 14.35-15.30 18 Clinical Outcomes 1: Psoriasis: IPC       17 3rd floor Hervé Bachelez
        001 Risk of Serious Infection Associated With Biologic Therapies in Psoriasis : a Prospective Cohort Study from the British Association of Dermatologists Biologic Interventions Register (BADBIR) Zenas Yiu      
        006 Abdominal obesity and insulin resistance are strongly associated with liver fibrosis in people with severe psoriasis. Catriona Maybury      
        009 PASI ≤ 2 corresponds to PASI 90, irrespective of baseline severity: A post-hoc analysis of the PRIME-study Nima Melzer      
        014 Apremilast in psoriasis - a prospective real-world study Igor Vujic      
        016 Psoriatic Arthritis and Hearing Loss Yevgeniy Semenov      
        017 Women, elderly and less educated psoriasis patients provide more 'not relevant' responses on the Dermatology Life Quality Index - is it a problem? Fanni Rencz      
        018 Kim-1 biomarker of kidney injury in patients with psoriasis Madalina Mitran      
        033 Clinical characteristics according to therapeutic efficacy of cyclosporine or methotrexate in patients with psoriasis vulgaris Eun-So Lee      
        036 The prevalence of periodontitis is increased in psoriasis and linked to its inverse subtype Clemens Painsi      
        037 Safety of Systemic Psoriasis Treatments evaluated in the Swiss Dermatology Network for Targeted Therapies (SDNTT) Julia-Tatjana Maul      
        040 HLA-B46 associates with sacroiliitis susceptibility in patients with psoriatic arthritis Kyoko Ikumi      
Friday 29 September 2017 14.35-15.30 19 Genetics and Cell Based Therapy 2: Epidermolysis bullosa       18 3rd floor Caterina Missero
        181 Local delivery of an antisense oligonucleotide for recessive dystrophic epidermolysis bullosa Ilse Haisma      
        182 Gene edition-mediated deletion of a mutation-containing COL7A1 exon 80 in epidermal stem cells of RDEB patients allows regeneration of normally adhesive skin Fernando Larcher      
        185 CRISPR/Cas9 mediated gene correction of COL7A1 Stefan Hainzl      
        186 CL2020, a human multilineage-differentiating stress enduring cells-rich product, has a potential to treat dystrophic epidermolysis bullosa. Yasuyuki Fujita      
        189 Improved safety profile: an efficient CRISPR/Cas9 double nicking approach for KRT14 repair in EB simplex Thomas Kocher      
        194 In vitro evaluation of QR-313; an anti-sense oligonucleotide designed to skip exon 73 from the COL7A1 mRNA Ilse Haisma      
        200 A Comparison of Minicircle Vectors Expressing COL7A1 Under the Control of Human Promoters for the Treatment of Recessive Dystrophic Epidermolysis Bullosa Fatma Alshehri      
        205 Altering the splice pattern of COL17A1 with antisense oligonucleotides Hannah Potocki      
        206 Nanomechanical properties of collagen VII anchoring fibrils in recessive dystrophic epidermolysis bullosa patients Balázs Mayer      
        209

Establishing a Cost-effective Strategy for Diagnosis of Inherited Epidermolysis Bullosa in Resource-limited Settings

Vamsi Yenamandra      
        560 Transcriptome profiling in recessive dystrophic epidermolysis bullosa patients Roland Zauner      
Friday 29 September 2017 14.35-15.30 20 Photobiology and Pigmentation 2: Effects of UV radiation       20 3rd floor Thomas Schwarz
        620 Poly(ADP-ribose) polymerase-1 activity modulates mitochondrial function following UVB irradiation Csaba Hegedüs      
        627 A single sunburn influences the immune component of human skin for up to 14 days Suzanne Pilkington      
        630 Multi-omics identify nuclear protein 1 (Nupr1/p8) as central regulator of redox stress mediated by ultraviolet A light. Florian Gruber      
        631 Photoprotective effect of Skin-derived Precursors on skin photodamage in Balb/c hairless mice Jianqiao Zhong      
        633 Stemness and differentiation potential-recovery effects of sinapic acid against ultraviolet-A-induced damage through the regulation of p38 MAPK and NF-kB Jongsung Lee      
        635 PUVA diminishes imiquimod-induced psoriatic phenotype with gene expression signature associated with senescence Nitesh Shirsath      
        636 The tryptophan photoproduct 6-formylindolo[3,2-b]carbazole sensitizes keratinocytes to UVA-induced apoptosis: Clues for a cytoprotective role of the aryl hydrocarbon receptor Katharina Rolfes      
        637 Time-dependent investigation of UVB-induced cellular mechanisms in human keratinocytes using mRNA encoding cyclobutane pyrimidine dimer-specific photolyase Margit Péter      
        639 The impact of ageing and chronic sun exposure on the biomechanical function and histological composition of black African-American skin Abigail Langton      
Saturday 30 September 2017 10.30-11.30 21 Epidermal Structure and Function 4: Clinical Aspects        01 2nd Floor Menno de Rie
        098 Novel amino acid duplication in collagen XVII causes mild junctional epidermolysis bullosa by altering the coiled-coil structure and impairing collagen XVII trimerization and maturation Jasmin Kroeger      
        102 Proteins causing autosomal congenital recessive ichthyosis (ARCI) colocalize in differentiated primary keratinocytes and the interactions are altered in cells from patients with TGM1 mutations Hans Törmä      
        107 Variation of the epidermal expression of glucocorticoid receptor-beta as predictive marker of bullous pemphigoid outcome Frank Antonicelli      
        108 Skin inflammation is associated with matrix remodelling and MMP expression and activation in hidradenitis suppurativa Frank Antonicelli      
        115 Opsins and cryptochromes in human epidermal keratinocytes: a perspective for blue light therapies Irene Castellano-Pellicena    
        117 Using a bivalent DNA aptamer to reduce blister formation in recessive dystrophic epidermolysis bullosa Thomas Lettner      
        119 Study on skin barrier function in cutaneous field cancerization in a murine model Juan Luis Santiago      
        124 Desmoplakin mutation in neonatal erythroderma Katariina Hannula-Jouppi      
        128 Ichthyosis patients with TGM1 mutations show aberrant transcriptomic expression Hanqian Zhang      
        131 Stressed out keratinocytes, new insights into psoriasis lesion formation Rosalind Hannen      
Saturday 30 September 2017 10.30-11.30 22 Hair and Other Adnexal Structures  2: Adnexal Structures        03 2nd Floor Mike Philpott
        247 Metabolic signaling in sebaceous gland homeostasis Klaus Göbel      
        250 Sweat Glands Shrink Upward with Aging, Causing Dermal Layer Defects That Lead to Loss of Skin Elasticity and Wrinkling   -Establishment of 3D Imaging Method for Skin Appendages- Tomonobu Ezure      
        256 Expression patterns of the Siah genes in postnatal mouse skin Andrey Panteleyev      
        258 11?-hydroxysteroid dehydrogenase type 1 inhibition attenuates the adverse effects of glucocorticoids on dermal papilla cells Ji Young Choi      
        260 Establishment and Characterization of Human Sebocytic Progenitor Cells that Can Differentiate into Functional Sebocytes Noriko Akimoto      
        262 OLR1 scavenger receptor knockdown affects mitotic gene expression but is dispensable for oxidized phospholipid- mediated stress signaling in SZ 95 sebocytes. Florian Gruber      
        267 Adiponectin signaling regulates lipid production in human sebocytes Jeung-Hoon Lee      
        270 The Clinical, Biochemistry and Biophysics signature of brittle nails Audrey Gueniche      
        271 Mutational spectrum in 39 Spanish patients with Hypohidrotic Ectodermal Dysplasia M Martinez      
Saturday 30 September 2017 10.30-11.30 23 Inflammation, Immunity and Infection 9: Psoriasis       05 2nd Floor Chris Griffiths
        100 Evaluation of pharmacological responses in a fully human ex vivo skin model following in situ T cell activation with Th17 / Th1 psoriasis-like phenotype Claire Jardet      
        120 POMP increases proteasome assembly and activity in psoriatic lesional skin Pierre-Emmanuel Stoebner    
        122 Changes in fatty acid lengths of ceramides toward shorter chain dominance in human psoriasis skin Bo-Kyung Kim      
        131 Stressed out keratinocytes, new insights into psoriasis lesion formation Rosalind Hannen      
        329 An investigation of the molecular pathogenesis of Generalized Pustular Psoriasis and its overlap with Psoriasis Vulgaris. Marika Catapano      
        342 Differential induction of ATF3 and HO-1 in myeloid cells and keratinocytes via Dimethylfumarate or Cyclosporine A Stefanie Müller      
        396 Ixekizumab Treatment Shows a Neutral Impact on the Glucose and Lipid Profile of Patients with Moderate-to-Severe Psoriasis: Results from UNCOVER-1,-2, and -3 Jashin Wu      
        397 Fifty two-week efficacy and safety results from SPIRIT-P1: A Phase 3 study of ixekizumab in patients with active psoriatic arthritis Philip Mease      
        398 Efficacy and Safety of Ixekizumab for the Treatment of Plaque Psoriasis: Results through 108 Weeks Randomised, Phase III Clinical Trial (UNCOVER-3) Andrew Blauvelt      
        411 CO-releasing fumarate complexes show superior anti-inflammatory effects compared to dimethyl fumarate treatment Britta Bauer      
Saturday 30 September 2017 10.30-11.30 24 Inflammation, Immunity and Infection 10       09 2nd Floor Bernhard Homey
        318 The functional characterization of CARD14 variants in pityriasis rubra pilaris affected skin and keratinocytes Anikó Göblös      
        328 Severe cutaneous HSV-2 infection at night time compared with at day time is due to upregulation of an HSV-2 receptor nectin-1 driven by CLOCK protein in mice Youichi Ogawa      
        333 Disclosing the interdependence: how obesity orchestrates skin disease Yuliya Skabytska      
        343 MMP9-mediated Semaphorin4D shedding from T cells orchestrates chemokine secretion and CD8+ T cell migration in oral lichen planus          Yao Ke      
        345 Tissue factor and protease-activated receptor-2 signaling control cutaneous inflammation in mice Maria Isabel Schmidgen      
        353 Anti–Saccharomyces cerevisiae antibodies (ASCA) are biomarkers of moderate-to-severe hidradenitis suppurativa (HS), but not of severe plaque psoriasis: Results from a prospective, multicenter study Jeremy Gottlieb      
        360 Interface Dermatitis is characterized by a type I immune response and an epidermal reaction to IFN-y and TNF-α Felix Lauffer      
        371 The antitumor effect of basic leucine zipper transcription factor ATF-like 2 through IL-12 p40 upregulation Hisashi Kanemaru      
        379 Granulocyte and monocyte adsorption apheresis is effective for refractory netrophilic disorders and induces myeloid-derived suppressor cells Takuro Kanekura      
        389 Therapeutic implication of IL-15Rα in Behçet’s disease mouse model Eun-So Lee      
Saturday 30 September 2017 10.30-11.30 25 Inflammation, Immunity and Infection 11: Atopic dermatitis       11 2nd Floor Martin Steinhoff
        114 11β-Hydroxysteroid Dehydrogenase 1 Expression in the Skin Might Have a Role in the Occurrence of Atopic Dermatitis Solam Lee      
        129 Aryl hydrocarbon receptor (AHR)-dependent expression of aldo-keto reductase (AKR) 1C3 in the lesions of atopic dermatitis Motoki Nakamura      
        367 CCL17 and CCL22 production induced by toll like receptor stimulation by monocyte-derived Langerhans cells in patients with atopic dermatitis Koichiro Nakamura      
        368 Interleukin-33 expression is elevated in the horny layer of patients with atopic dermatitis Naomi Nakamura      
        401 The inhibitory effect of a histamine 4 receptor antagonist on chemokine production by monocyte-derived Langerhans cells in patients with atopic dermatitis Koichiro Nakamura      
        403 Comparative approach to assess the genetic background of inflammation in atopic dermatitis and psoriasis Ulrike Wehkamp      
        404 MOR106, an anti-IL17C antibody, reduces severity of atopic dermatitis-like skin inflammation in Flaky Tail model Nick Vandeghinste      
        406 Skin barrier function genes differentially correlated to resident Staphylococci in lesional and non-lesional skin in atopic eczema Matthias Reiger      
        408 Up-regulation of the production of CCL18, a chemokine related to atopic dermatitis, by Th2 cytokines and by histamine H2- or H4 receptor agonists on human M2c- and M2a macrophages Susanne Mommert      
        412 Atopic dermatitis and filaggrin deficiency lead to characteristic shifts of skin microbiome Hansjörg Baurecht      
        414 Influence of filaggrin genotype on regulatory T cells in atopic dermatitis Verena Moosbrugger-Martinz    
Saturday 30 September 2017 10.30-11.30 26 Wound Healing and Tissue Remodelling 2       12 2nd Floor John Connelly
        665 6-formylindolo[3,2-b]carbazole (FICZ) accelerates skin wound healing via activation of ERK, but not aryl hydrocarbon receptor Hiroshi Uchi      
        668 Activation of Nrf2 promotes wound healing by expansion of hair follicle stem cell populations Sukalp Muzumdar      
        669 Senescence-associated secretion of vesicular miR-23a-3p and its impact during the paracrine crosstalk of dermal and epidermal cells Vera Pils      
        670 Development of high-throughput cell migration assay using tuneable micro-engineering substrates Filipe Almeida      
        675 Electric current-induced lymphatic activation Kentaro Kajiya      
        677 Low-dose calcipotriol as a therapeutic option to improve wound healing in epidermolysis bullosa Christina Gruber      
        679 Wound Healing properties of OPAL A (patented Carica papaya fruit extract) Reddy Sreekanth Vootukuri    
        680 New 3D reconstructed hypodermis model without substrate to evaluate adipose tissue remodeling Aurelie courtois      
        681 Detection of the olfactory receptor OR6V1 in cutaneous cell types in vitro and ex vivo Paraskevi Gkogkolou      
        684 Benefits of mineralocorticoid receptor antagonism in cutaneous wound healing Van Tuan Nguyen      
Saturday 30 September 2017 10.30-11.30 27 Melanoma and other Skin Cancers 3: Melanoma        16 3rd floor Christian Posch
        021 Clinical and genetic characteristics of cutaneous melanoma with clinical history of early childhood onset Akane Minagawa      
        553 Folate hydrolase-1 is a novel player and target for antibody-based brachytherapy in malignant melanoma Barbara Meier      
        555 c-Rel Suppression Influences Cell Cycle Regulation of Human Melanoma Cells Verena Lorenz      
        557 Influence of programmed cell death-1 immune checkpoint blockade on T cell profile and response to melanoma-associated antigen in advanced malignant melanoma patients Ryo Takahashi      
        559 Epidemiology of malignant melanoma in Japan: analysis of 4239 patient data. Yasuhiro Fujisawa      
        562 Sensitivity of melanoma cell lines to combination of mefloquine and vemurafenib Diana Panayotova-Dimitrova    
        563 Establishment of in vivo and in vitro mouse models relevant for human cutaneous melanoma mutated for NRAS Valerie Petit      
        564 Role of CC-chemokine Receptor 6 (CCR6) and CC Ligand 20 (CCL20) mediated immunosurveillance in malignant melanoma Diego Martin-Garcia      
        565 Effects of melanoma derived exosomes on peritumoral stromal cells Tünde Buknicz      
        569 Lipidomic Biomarkers for Melanoma Arantza Perez-Valle      
Saturday 30 September 2017 10.30-11.30 28 Melanoma and other Skin Cancers 4: Epithelial Tumors; miscellaneous aspects       17 3rd floor Anissa Chikh
        536 Sonidegib Duration of Response Across 30 Months: Results from the Randomized Phase 2 BOLT Trial Leonard Lionnet      
        542 Sonidegib Tolerability Across 30-Months: Results from the Phase 2 Randomized BOLT Trial Leonard Lionnet      
        545 Shedding of collagen XVII accelerates tumor growth and invasion in skin carcinogenesis Claus-Werner Franzke      
        548 Viral antigen-specific pre-vaccination prevents engraftment of tumor cells expressing the cognate antigen in mice Victoria Leb-Reichl      
        549 Targeting human skin SCC growth and metastasis at different stages of progression Purificación Muñoz      
        558 Multiple functionally distinct memory T cell subtypes are present in cutaneous squamous cell carcinoma Chester Lai      
        561 Extracellular vesicles as biomarkers for the detection of epidermolysis bullosa-associated squamous cell carcinoma Josefina Piñón Hofbauer      
        566 Elucidating the role of caveolin-2 in squamous cell carcinoma development Andrew Overmiller      
        570

Mammary Paget’s Disease - Case Report

Vasile Benea      
Saturday 30 September 2017 10.30-11.30 29 Clinical Outcomes 2: Acne, atopic dermatitis and other diseases       18 3rd floor Robert Swerlick
        003 Crisaborole Ointment Improves Global Atopic Dermatitis Severity: Pooled Results From Two Phase 3 Clinical Trials Joseph Fowler      
        008 Congenital Anomalies in Neurofibromatosis 1: A retrospective register-based total population study Jussi Leppävirta      
        010 How to predict allergic contact dermatitis accompanied in patients with atopic dermatitis Solam Lee      
        012 Crisaborole Ointment Provides Early Relief of Pruritus in Two Phase 3 Clinical Trials in Patients With Mild or Moderate Atopic Dermatitis Emma Guttman-Yassky      
        013 Pigmentosa xeroderma group D: a clinical and genetic study of 19 Japanese cases Hideaki Tanizaki      
        026 Nationwide investigation of hidradenitis suppurativa in Japan Koremasa Hayama      
        028 Is suction blister epidermal grafting a simple and reliable way to screen patients with large area vitiligo for ReCell treatment ? Zhifei Liu      
        029 Internalized Stigma in Acne Vulgaris, Vitiligo and Alopecia Areata Asli Bilgic Temel      
        032 Efficacy and safety of anti-bacterial/anti-inflammatory microneedle patch for the treatment of mild to moderate acne vulgaris: a randomized, double-blind study Minkyung Lee      
        035 Experiences with Smo antagonist vismodegib for the treatment of locally advanced basal cell carcinoma Norbert Kiss      
        041 Prevalence, characteristics and burden of pruritus in chronic dermatoses Tomasz Hawro      
Saturday 30 September 2017 10.30-11.30 30 Clinical Outcomes 3: Bullous diseases and other entities       20 3rd floor Alain Hovnanian
        015 The impact of pemphigus on health-related quality of life: first results with the EQ-5D questionnaire Fanni Rencz      
        020 Responsiveness, Minimal Clinically Important Difference (MCID), and cut-offs for the Pemphigus Disease Area Index (PDAI) and Autoimmune Bullous Skin disorder Intensity Score (ABSIS) for Pemphigus Sarah Hanna      
        022 Randomized, Double-Blind, Placebo-Controlled, Single-Centre, Phase I Safety Study of Intradermal Injections of Autologous Fibroblasts Isolated from the Non-Bulbar Dermal Sheath of the Hair Follicle to Treat Skin Aging Susanne Grether-Beck      
        024 Development and Validation of an Investigators Global Assessment Scale to Evaluate Overall Disease Severity in Patients with Epidermolysis Bullosa Simplex Alain Hovnanian      
        025 Preventive effects of topical washing with miconazole nitrate-containing soap to diaper candidiasis in the hospitalized elderly patients: a prospective, double-blind, placebo-controlled study Hidenori Takahashi      
        027 Lichen Sclerosus in Pregnancy: A Review of 33 Cases Yvonne Nguyen      
        030 Efficacy and safety of botulinum toxin B injection for Raynaud’s phenomenon and digital ulcers in patients with systemic sclerosis: single-blind, randomized trial Buddhini Perera      
        031 Topically applied diacerein: Basic pharmacokinetics in generalized-severe epidermolysis bullosa simplex Michael Ablinger      
        034 Surgical wound healing in patients with epidermolysis bullosa Adam Harris      
        038 Therapeutic efficacy of IL-17 blockade identifies lichen planus as a Th17-driven skin disorder Farzan Solimani      
        039 Autoreactive B-cells phenotype analysis in pemphigus patients before and after anti-CD20 treatment Maud Maho Vaillant