Concurrent Session 2: Epidermal Structure & Function

Date: Thursday 28 September 2017
Time: 14.20-15.45
Room: Mozart Hall 1-3

Chairs: Johanna Brandner, Sara Brown

Concurrent talks are 8 minutes plus 2 minutes discussion.

Program

14.20-14.30

019 (Poster 090)
The N -terminal domain of Filaggrin 2 co-localizes, binds to and activates the Skin aspartic acid protease in the epidermis of human skin
M Donovan,1 A Thomas-Collignon,2 L Simonetti,1 S Desbouis,1 C Collin-Djangoné,1 C Reverdy,3 J Rain,3 E Formstecher3 and D Bernard1 1 L’Oréal R&I, Aulnay sous Bois, France, 2 CNRS, Gif sur Yvette, France and 3 Hybrigenics Services, Paris, France

14.30-14.40 020 (Poster 084)
The keratin cytoskeleton as a regulator of keratinocyte mechano-sensing

A Laly and J Connelly Centre for Cell Biology and Cutaneous Research, Blizard Institute - Barts and The London School of Medicine and Dentistry, London, United Kingdom
14.40-14.50 021 (Poster 097)
iRHOM2 regulation of loricrin in the epidermal barrier
L McGinty, DP Kelsell and D Blaydon Centre for Cell Biology and Cutaneous Research, Queen Mary University of London, London, United Kingdom
14.50-15.00 022 (Poster 085)
Type XVII collagen suppresses interfollicular epidermal proliferation in neonatal and aged skin, and helps rejuvenate epidermis

M Watanabe,1 K Natsuga,1 W Nishie,1 G Donati,4 Y Fujimura,1 T Tsukiyama,2 H Ujiie,1 M Ozaki,3 FM Watt4 and H Shimizu1 1 Department of Dermatology, Hokkaido University Graduate School of Medicine, Sapporo, Japan, 2 Department of Biochemistry, Hokkaido University Graduate School of Medicine, Sapporo, Japan, 3 Department of Biological Response and Regulation, Faculty of Health Sciences, Hokkaido University, Sapporo, Japan and 4 Centre for Stem Cells and Regenerative Medicine, King’s College London, London,
United Kingdom
15.00-15.10 023 (Poster 092)
BNIP3-induced autophagy is required for maintenance of epidermal homeostasis

M Moriyama, H Kubo, T Morita, T Hayakawa and H Moriyama Pharmaceutical Research and Technology Institute, Kindai University, Higashi-Osaka, Japan
15.10-15.20 024 (Poster 079)
Inactivation of DNase1L2 and DNase2 in keratinocytes suppresses DNA degradation during epidermal cornification and results in constitutive parakeratosis

H Fischer, M Buchberger, E Tschachler and L Eckhart Department of Dermatology, Medical University of Vienna, Vienna, Austria
15.20-15.30 025 (Poster 076)
Chromatin architectural protein CTCF controls terminal keratinocyte differentiation, epidermal barrier maintenance and suppresses inflammatory responses in the skin

I Malashchuk,1 J Rudolf,1 T Vafaee,1 K Poterlowicz,1 A Sharov,2 MY Fessing,1 AN Mardaryev1 and V Botchkarev1,2 1 Centre for Skin Sciences, University of Bradford, Bradford, United Kingdom and 2 Department of Dermatology, Boston University, Boston, MA
15.30-15.40 026 (Poster 091)
5C analysis reveals distinct spatial contact networks between gene-rich and gene-poor TADs at the Epidermal Differentiation Complex in skin epithelial cells

K Poterlowicz,1 J Yarker,1 I Malashchuk,1 AN Mardaryev,1 MR Gdula,2 A Sharov,3 T Kohwi-Shigematsu,4 V Botchkarev1 and MY Fessing11 University of Bradford, Bradford, United Kingdom, 2 Biochemistry, University of Oxford, Oxford, United Kingdom, 3 Boston
University School of Medicine, Biston, MA and 4 University of California San Francisco, San Francisco, CA